Research Article
Altered Esophageal Mucosal Structure in Patients with Celiac Disease
Table 1
Characteristics of the study population.
| | Subjects | CD
| GERD
| Asymptomatic controls,
| value |
| | Age, median (range) | 28 (18–73) | 44 (24–68) | 36 (28–62) | 0.04 | | Female, number (%) | 17 (68) | 5 (45) | 3 (60) | 0.41 | | BMI, mean (SD) | 23 (3) | 24 (2) | 25 (2) | 0.23 | | a-tTG IgA, mean (SD) | 189 (125) | 2 (0) | 2 (1) | <0.001 | | a-DGP IgG, mean (SD) | 88 (116) | 3 (2) | 0 (1) | <0.001 | |
a-DGP IgA, mean (SD) | 129 (49) | 7 (3) | 1 (1) | <0.001 | | Smokers, number (%) | 2 (8) | 1 (2) | 3 (27) | 0.15 | | Alcohol (units/week), mean (SD) | 1 (1.9) | 1.2 (1.4) | 3.8 (4.7) | 0.18 | | Hiatal hernia size (cm), mean (SD) | 1 (1) | 1 (1) | | 0.86 | | Esophagitis, number (%) | 3 (12) | 2 (11) | | 0.99 | | Endoscopic grading flap valve (Abnormal Hill), number (%) | 8 (32) | 7 (37) | | 0.74 | | Intestinal mucosal damage, number | | | | | | Marsh IIIa | 1 | | | | | Marsh IIIb | 6 | | | | | Marsh IIIc | 18 | | | |
|
|
CD versus controls; Mann-Whitney test.
|
