The Utility of Fecal Calprotectin in the Real-World Clinical Care of Patients with Inflammatory Bowel Disease

Table 4

Association of FCAL results with serological markers, endoscopy, and radiography.

Diagnostic test	Disease activity	FCAL positive	FCAL negative	value	Odds ratio
					95% CI
MRE/CTE	Active	6	3	0.31
	Inactive	5	9
Endoscopy	Active	17	4	0.01	8.79
	Inactive	4	9		1.54–65.55
Albumin	Low	17	3	0.015	4.66
	Normal	71	59		1.26–26.06
Hg	Low	40	16	0.0059	2.74
	Normal	48	53		1.31–5.96
CRP	Elevated	28	8	0.006	3.46
	Normal	48	48		1.36–9.73
PGA	Remission	21	42	0.00004	3.68
	Active	78	42		1.86–7.48

Low hemoglobin (Hg, anemia) is defined as per our local laboratory values which is consistent with WHO definition of anemia with one difference that adult male Hg < 130 g/L (male age ≥ 15 yr Hg < 140 g/L, female age ≥ 15 yr Hg < 120 g/L, children 12–14 yr Hg < 120 g/L, and children 4–11 yr Hg < 115 g/L).
(i) PGA: Physician’s global assessment.