Research Article
Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease
Table 1
Clinical and demographic characteristics of patients.
| | | Chronic hepatitis
() | Cirrhosis
() | HCC
() |
| | Age, years (mean SD (range)) | 43.9 ± 12.7 (25–68) | 64.9 ± 11.0 (46–89) | 61.3 ± 9.9 (50–77) |
| | Male sex (%) | 40 (69%) | 35 (76.1%) | 20 (95.2%) |
| | Cause of liver disease (, %) | | | | | HBV infection | 28 (48.3%) | 11 (23.9%) | 9 (42.9%) | | HCV infection | 30 (51.7%) | 14 (30.4%) | 5 (23.8%) | | Alcohol | | 14 (30.4%) | | | Unknown | | 7 (15.2%) | 7 (33.3%) |
| | Histological grade () | | | | | Mild necroinflammation (1–6) | 23 (67.6%) | NA | NA | | Moderate (7–12) | 9 (26.5%) | NA | NA | | Severe (13–18) | 2 (7.9%) | NA | NA |
| | Histological stage () | | | | | No fibrosis (0) | 14 (41.2%) | NA | NA | | Minimal (1-2) | 9 (26.5%) | NA | NA | | Moderate (3-4) | 7 (20.5%) | NA | NA | | Severe (5-6) | 4 (11.8%) | NA | NA |
| | MELD score (mean ± SD (range)) | NA | 15.89 ± 9.27 (3–43) | |
| | Liver stiffness (kPa) (mean ± SD (range)) | 7.91 ± 1.68 (5–11) | 33.11 ± 13.22 (22–66) | NA |
|
|
NA: not applicable.
|
