The Utility of Endoscopic Biopsies in Patients with Normal Upper Endoscopy
Table 3
Pathological diagnosis on biopsy of normal upper GI tract and cost per positive finding.
Pathological finding
Abnormal histology (%) (absolute number)
Cost/positive finding ( CAD)
Esophagus
Reflux esophagitis
16% (81/502)
489
Eosinophilic esophagitis
3% (13/502)
2963
Barrett’s esophagus
1% (4/502)
8889
Stomach
Chronic gastritis
23% (243/1054)
351
Chronic gastritis with IM
4% (42/1054)
2282
HP gastritis
6% (62/1054)
1404
HP gastritis with IM
1% (12/1054)
6086
Reactive gastropathy
7% (69/1054)
1217
Reactive changes
1% (15/1054)
6086
Duodenum
Increased IEL
6% (54/918)
450
Duodenitis
2% (22/918)
3501
Celiac disease
3% (25/918)
3024
Lymphoid hyperplasia
0.5% (5/918)
16631
IM = intestinal metaplasia, HP = Helicobacter pylori, and IEL = intraepithelial lymphocytes. The percentages expressed in this table identify the yield of the diagnosis in patients with macroscopically normal EGDs that were biopsied.
