Clinical Study

Eosinophilic Esophagitis in Children and Adolescents with Abdominal Pain: Comparison with EoE-Dysphagia and Functional Abdominal Pain

Table 1

Clinical features of patients with eosinophilic esophagitis and functional abdominal pain.

EoE-D (%)EoE-AP (%)FAP (%)EoE-D versus EoE-AP ()EoE-AP versus FAP ()

Sex (%)
 Male58 (90.6)49 (77.8)26 (42.6)0.054<0.001
 Female6 (9.4)14 (22.2)35 (57.4)

Mean age, yr (range) at diagnosis11.7 (3–17)9.44 (2–17)10.87 (4–17)

Mean duration of FU, yr. (range)3.4 (0.5–7.8)5.5 (0.4–8.8)4.8 (0.5–5.4)

Presenting symptoms, number (%)
 Dysphagia64 (100)1 (1.6)0 (0)0.000.50
 Abdominal pain8 (12.1)63 (100)61 (100)0.000.07
 Nausea11 (16.7)29 (45.3)27 (44.3)0.000.10
 Vomiting12 (18.2)11 (17.2)1 (1.6)0.160.00
 Regurgitation5 (7.6)7 (11.1)3 (4.9)0.190.12
 Heartburn7 (10.6)6 (9.5)1 (1.6)0.210.05
 Diarrhea 4 (6.25)7 (11.1)1 (1.6)0.510.075

Some patients had more than one presenting symptom.
Patient initially presented with dysphagia; however subsequent visits showed abdominal pain as primary cause for distress.
Abdominal pain was central or generalized.