Research Article
A Canadian Study toward Changing Local Practice in the Diagnosis of Pediatric Celiac Disease
Table 1
Baseline and follow-up comparisons between diagnostic groups.
| | | Serological diagnosis () | Biopsy diagnosis () | value |
| Baseline | Age (years)1 | 8.6 (3.5) | 9.2 (3.5) | 0.38 | Gender (M : F) | 16 : 24 | 18 : 30 | 0.81 | Height -score1 | (1.04) | 0.05 (0.99) | 0.66 | Weight -score1 | (1.00) | 0.04 (1.03) | 0.73 | aTTG (U/mL)2 | 595 (200–4100) | 42 (7.8–2500) | <0.001 | GI symptoms | 87.5% | 85% | 1.0 | Anemia/fatigue | 65% | 54% | 0.38 | Symptoms | | | | Family history | 47.5% | 43% | 0.67 |
| | | () | () | | Follow-up | Diagnosis to follow-up (months)1 | 11.0 (3.8) | 11.7 (12.16) | 0.42 | Age (years)1 |
9.5 (3.5) () |
10.5 (3.7) | 0.26 | Gender (M : F) | 14 : 18 | 16 : 25 | 0.97 | Height -score1 | (1.04) | 0.10 (1.00) | 0.42 | Weight -score1 | (0.93) | 0.10 (1.07) | 0.37 | GFD adherence | 94% | 93% | 0.43 | Symptom improvement | 93% | 85% | 0.52 | aTTG (U/mL)2 | 9.4 (1–98) | 4.0 (1–420) | 0.005 | % aTTG decline2 | 98.5 (90.7–99.9) | 91.4 (308–99.8) | <0.001 | aTTG < 7 U/mL% | 40% | 72% | 0.013 |
|
|
Mean (standard deviation); median (range).
|