Research Article

Clinical Trial Risk in Hepatitis C: Endpoint Selection and Drug Action

Figure 5

Success rate based on drug class. Clinical trial success rates in hepatitis C based on the drug class, being either a small molecule drug or a biologic. The transition probabilities for each phase as well as the cumulative pass rates were calculated. It is apparent that there are many more small molecule drugs in development and they have a much higher cumulative pass rate than biologics.