Functional Capacity, Respiratory Muscle Strength, and Oxygen Consumption Predict Mortality in Patients with Cirrhosis
Table 2
Univariate and multivariate analysis of the variables under study.
Variable
Not adjusted analysis
Adjusted analysis
HR (95% CI)
value
HR (95% CI)
value
Age
1.05 (0.97–1.14)
0.182
1.02 (0.91–1.14)
0.742
Gender
Female
1.0
Male
0.6 (0.26–1.76)
0.426
Child-Pugh
Class A
1.0
Class B
1.65 (0.27–9.86)
0.584
1.55 (0.19–13.7)
0.665
Class C
17.9 (3.98–80.8)
0.01
3.42 (0.35–35.8)
0.288
MELD
1.33 (1.11–1.60)
0.02
1.22 (0.81–1.6)
0.251
6MWT
0.83 (0.77–0.91)
<0.01
0.80 (0.72–0.96)
0.002
VO2peak
0.45 (0.33–0.67)
<0.01
0.70 (0.55–0.86)
0.001
MIP
0.75 (0.65–0.77)
<0.01
0.82 (0.77–0.94)
0.002
MEP
0.83 (0.73–0.91)
<0.01
1.06 (0.87–1.5)
0.525
MELD: model for end-stage liver disease, 6MWT: six-minute walk test, : peak oxygen consumption, MIP: maximum inspiratory pressure, and MEP: Maximum Expiratory Pressure. HR = hazard ratio; analysis adjusted by age, Child-Pugh score, MELD, 6MWT, , MIP, and MEP ().
