Distribution of Hepatitis C Risk Factors and HCV Treatment Outcomes among Central Canadian Aboriginal

Table 1

Baseline characteristics of HCV infection according to Aboriginal status.

	Aboriginal ()		Non-Aboriginal ()		Total ()		value
	Mean/%	SD	Mean/%	SD	Mean/%	SD
Continuous variables
Age	45.6	9.4	49.6	11.2	49.5	11.1	0.010
Weight (kg)	80.1	16.4	78.1	17.7	78.1	17.6	0.437
HCV RNA (IU/mL)							0.967
ALT (IU/L)	97.3	83.7	93.6	99.6	93.7	99.2	0.786
AST (IU/L)	79.1	101.0	67.6	63.7	67.9	65.0	0.206
Fibroscan score	2.4	1.3	1.8	1.3	1.9	1.3	0.227
Biopsy stage (Metavir)	2.2	1.1	2.0	1.1	2.0	1.1	0.287
Biopsy grade (Metavir)	2.0	0.7	1.9	0.7	1.9	0.7	0.563
Fibrosis progression per year	0.151	0.168	0.126	0.254	0.126	0.252	0.625
Number of HCV risk factors	4.2	1.8	3.1	2.1	3.1	2.1	<0.001
Categorical variables
Women	36.4		31.7		31.9		0.466
Genotype							0.437
1	68.5		65.4		65.5
2	7.4		8.6		8.5
3	22.2		18.0		18.1
4	0.0		5.6		5.5
5	1.9		2.4		2.4
Four or more HCV risk factors	67.3		45.1		45.7		0.001
Material deprivation (quintile)							0.023
Least deprived	5.9		25.4		24.8
2	19.6		20.2		20.2
3	23.5		16.6		16.8
4	19.6		15.4		15.5
Most deprived	31.4		22.4		22.7
Social deprivation (quintile)							0.227
Least deprived	2.0		9.7		9.5
2	21.6		14.5		14.7
3	11.8		13.4		13.4
4	15.7		19.2		19.1
Most deprived	49.0		43.1		43.3
Low income neighbourhood	48.1		34.1		34.5		0.032
Poor neighbourhood housing suitability	43.1		32.9		33.2		0.127
Medium/large urban population centre	67.3		75.0		74.8		0.192
Rural area	21.8		14.9		15.1		0.16