Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups

Figure 1

Comparison of the degree/stage of eosinophil-rich inflammation on the biopsies of EoE-D and EoE-AP patients. MAB: microabscess, SLE: superficial layering, ED: epithelial desquamation, BZH: basal zone hyperplasia, RPE: rete pegs elongation, SP: spongiosis or increased intracellular space, FB: lamina propria fibrosis, DFE: diffuse or focal distribution, E-Dist: distribution around rete pegs, and DE: degranulation. Fibrosis (FB) was evaluable in 57 (EoE-D) and 54 (EoE-AP) patients and was positive in 41 (71.9%) and 37 (68.5%), respectively, value 0.85 (Chi-square test on 1 df = 0.03, = 0.85). Statistically significant.