Serum Albumin Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis

Table 1

Baseline clinical characteristics and outcomes among patients with different albumin levels.

Characteristic	Normal; ()	Hypoalbuminemia		value
		Mild ()	Severe ()
Median age, years (IQR)	46.5 (37–60)	50 (39–67)	47.5 (36–70)	0.012
Male sex, (%)	273 (64.4)	116 (58.6)	46 (59.0)	0.316
Time from pain onset to admission (days)				<0.001
BMI ≥ 30, (%)	23 (5.4)	12 (6.1)	4 (5.1)	0.934
Etiology
Biliary, (%)	198 (46.7)	87 (43.7)	23 (30.0)	0.024
Alcohol, (%)	56 (13.2)	29 (14.6)	11 (14.3)	0.888
Hypertriglyceridemia, (%)	21 (5.0)	8 (4.0)	8 (10.1)	0.094
Idiopathic, (%)	145 (34.2)	68 (34.2)	33 (42.9)	0.323
Other, (%)	9 (2.1)	9 (4.5)	4 (5.2)	0.153
Chronic concomitant diseases	240 (56.6)	116 (58.3)	53 (68.8)	0.134
Neurologic, (%)	4 (0.9)	1 (0.5)	5 (0.5)	0.004
Cardiovascular, (%)	13 (3.1)	13 (6.5)	4 (5.2)	0.126
Pulmonary, (%)	5 (1.2)	4 (2.0)	2 (2.6)	0.385
Diabetes mellitus, (%)	66 (15.6)	27 (13.6)	12 (15.6)	0.800
Hypertension, (%)	92 (21.7)	48 (24.1)	20 (26.0)	0.365
Hepatitis virus carrier, (%)	16 (3.8)	7 (3.5)	2 (2.6)	0.721
Fatty liver, (%)	162 (38.2)	63 (31.7)	27 (35.1)	0.279
Laboratory findings
Hematocrit	0.43 (0.38–0.46)	0.41 (0.37–0.45)	0.40 (0.37–0.45)	0.001
Bilirubin, mg/dL (IQR)	1.17 (0.82–1.70)	1.23 (0.82–1.81)	1.053 (0.64–1.81)	0.805
ALT, U/L (IQR)	43 (21–160)	34 (16–92)	36 (19–57)	0.001
Glucose, mg/dL (IQR)	139 (114–182)	150 (119–200)	171 (117–216)	0.003
BUN, mg/dL (IQR)	12.7 (10.1–16.2)	15.1 (11.2–19.6)	16.0 (10.6–29.4)	<0.001
Outcomes
Median hospital days (IQR)	9 (7–12)	11 (8–14)	13 (9–21)	<0.001
Organ failure (%)	15 (3.5)	20 (10.1)	33 (42.3)	<0.001
Death, (%)	1 (0.2)	3 (1.5)	7 (9.0)	<0.001

may have more than one etiology. may have more than one chronic concomitant disease.