Table of Contents Author Guidelines Submit a Manuscript
Canadian Journal of Gastroenterology and Hepatology
Volume 2017, Article ID 6138105, 11 pages
Research Article

Disability in Patients with Inflammatory Bowel Disease: Correlations with Quality of Life and Patient’s Characteristics

Department of Gastroenterology, University Hospital of Larissa, Mezourlo 1, 41110 Larissa, Greece

Correspondence should be addressed to Konstantinos Argyriou; ku.gro.srotcod@2ransok

Received 22 January 2017; Revised 8 May 2017; Accepted 15 May 2017; Published 29 May 2017

Academic Editor: Michael Beyak

Copyright © 2017 Konstantinos Argyriou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Inflammatory bowel diseases may cause significant disability. However, little is known regarding the life domains where patients encounter most limitations. Objectives. To assess patients’ overall disability and determine the life domains where most restrictions were applied. Secondarily, we sought for possible relationships among disability, quality of life (HRQoL), and population characteristics. Method. The study lasted for two years (2013–2015) and included 200 patients from a referral centre. Disability was evaluated using the 36-item version of WHODAS 2.0 questionnaire. The influence of population characteristics on overall disability was assessed with linear regression. Results. Crohn’s disease (CD) patients showed greater overall disability compared to UC (19.22 versus 15.01, ), with higher scores in the domains of relationships, life activities, and participation. Disability was negatively associated with HRQoL (). Long activity, extensive disease, rural residence, and employment independently influenced the overall disability in both groups. Additionally, significant influence was recorded for lower education in the UC and for operation and celibacy in the CD group. Conclusions. CD patients were facing more limitations compared to those with UC, especially in the domains of relationships, activities, and participation. Other than clinical factors, sociodemographic characteristics were also associated with increased disability.