Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease
Table 2
Liver stiffness measurements and selected biochemical, hematological, and liver imaging parameters according to lifetime drinking history.
Nondrinker
Light drinker
Moderate drinker
Crude p value
Adjusted p value
LSM kPa
All
8.4 ± 8.0
9.8 ± 7.1
10.7 ± 12.5
0.570
0.546
Male
8.7 ± 10.1
8.0 ± 4.8
12.0 ± 13.4
0.226
0.639
Female
8.2 ± 5.1
12.4 ± 9.8
4.6 ± 1.7
0.053
0.016
LSM ≥ 8.2 kPa
All
12 (29)
24 (40)
10 (30)
0.459
0.302
Male
5 (24)
14 (35)
10 (37)
0.584
0.581
Female
7 (35)
10 (50)
0 (0)
0.092
0.132
CAP (dB/m)
322.1 ± 68.5
333.4 ± 54.2
340.6 ± 59.5
0.910
0.492
ALT (IU/ml)
36.4 ± 26.4
38.4 ± 29.5
37.4 ± 15.8
0.909
0.818
AST (IU/ml)
29.0 ± 17.6
28.6 ± 26.1
24.7 ± 11.2
0.606
0.457
GGT (IU/ml)
44.2 ± 42.9
53.6 ± 83.1
47.6 ± 45.4
0.738
0.750
Platelets (×109)
242.0 ± 62.6
229.5 ± 58.7
255.0 ± 45.6
0.095
0.081
Albumin (g/dL)
40.4 ± 2.8
40.6 ± 2.7
41.0 ± 3.4
0.704
0.601
Spleen size (cm)
10.6 ± 2.9
10.4 ± 2.9
9.9 ± 3.1
0.666
0.617
Liver size (cm)
17.3 ± 3.5
17.0 ± 2.3
17.9 ± 3.4
0.501
0.502
Data presented continuously (mean ± standard deviation) and analyzed using one-way ANOVA. Data presented categorically (n, %) and analyzed using Pearson’s χ2 test, unless specified. Smaller cohort of patients as LSM met quality criteria in 134 patients. Data presented categorically (n,%) and analyzed using Fisher’s exact test.Spleen size documented in 99 patients. Liver size documented in 94 patients.All p values adjusted for age and BMI unless specified. ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase.
