Treatment Algorithm for Chronic Idiopathic Constipation and Constipation-Predominant Irritable Bowel Syndrome Derived from a Canadian National Survey and Needs Assessment on Choices of Therapeutic Agents

Figure 2

(a) Respondents’ satisfaction with treatment options for managing patients with CIC. Stool softeners and stimulant laxatives () were found to be unsatisfying treatments for CIC compared to other options. On the other hand, GCC agonist (), osmotic laxatives (), 5-HT4 agonist (), and fibre supplements/bulking agents () were considered to be satisfying treatments for CIC among the treatment options being surveyed. (CIC: chronic idiopathic constipation; GCC: guanylyl cyclase C.) (b) Respondents’ satisfaction with treatment options for managing patients with IBS-C. Both stool softeners () and stimulant laxatives () were unsatisfying treatments for IBS-C compared to other options, whereas GCC agonist (), osmotic laxatives (), 5-HT4 agonist (), and fibre supplements/bulking agents () were considered to be satisfying treatments for IBS-C among the treatment options being surveyed. (IBS-C: constipation-predominant irritable bowel syndrome; GCC: guanylyl cyclase C).

(a)

(b)