Increased CCRPD-CXCRCD T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection

Table 2

Clinical characteristics of 4 subgroups of patients with chronic HBV infection.

	IT	IC	LR	RA	p-value
Subjects, n	19	20	18	20	/
Gender, males/females	10/9	12/8	11/7	12/8	0.950
Age, y	29(18-52)	29(18-56)	41.5(18-71)	42(24-65)	0.002
ALT, IU/L	27(16-38)	293(85-939)	25.5(15-34)	332(57-942)	<0.001
AST, IU/L	28(13-38)	129(51-491)	22(19-34)	177.5(39-915)	<0.001
HBV DNA, log10 IU/mL	7.87(6.45-8.38)	7.76(3.72-8.23)	2.36(0-3.20)	5.51(2.00-8.23)	<0.001
HBsAg, log10 IU/mL	4.557(3.495-4.54)	3.85(2.85-4.60)	2.69(1.35-3.53)	3.32(1.30-4.61)	<0.001
HBeAg, positive/negative, n	19/0	20/0	0/18	0/20	<0.001
ALT, elevated/normal, n	0/19	20/0	0/18	20/0	<0.001

(a) Values are expressed as median (minimum-maximum) for age, ALT, AST, and HBV DNA.
(b) HBV DNA<100 was treated as 0 log10 IU/ml.
(c) HBsAg<20 was treated as 20.