Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough

Figure 2

The dynamic course of immune function in evolving cirrhosis: cirrhosis-associated immune: (a) early cirrhosis sets the stage for ACLF; (b) evolving cirrhosis primes the systemic immune system and finally culminates in ACLF (c).

(a)

(b)

(c)