Alpha-Fetoprotein as a Predictive Marker for Patients with Hepatitis B-Related Acute-on-Chronic Liver Failure

Table 2

Univariate and multivariate Cox regression analysis for survival.

Parameter	Univariate Cox regression ()			Multivariate Cox regression ()
		HR	CI		HR	CI
Age	0.003	1.033	1.011 1.056	<0.001	1.041	1.019 1.063
Total bilirubin	<0.001	1.004	1.002 1.006	<0.001	1.004	1.002 1.006
INR	0.001	1.564	1.200 2.039	0.015	1.446	1.074 1.948
	<0.001	2.908	1.603 5.274	0.018	2.155	1.139 4.076
Ascites^#	0.407
HE^#	0.163

AFP, alpha-fetoprotein; INR, international normalized ratio; HE, hepatic encephalopathy; HR, hazard ratio; and CI, confidence interval; continuous variables and ^#categorical variables ( was sorted into subgroups: ≥ 2 and < 2. No statistical significance was attained between patients with or without ascites and HE).