Preoperative Thrombocytopenia May Predict Poor Surgical Outcome after Extended Hepatectomy
Table 2
Clinicopathologic characteristics of patients with a preoperative platelet count of <150 x 109/L.
Variables
Total
(n = 17)
Age (years)
63.1 ±12.5
Gender
Female/male
8/9
BMI (kg/m2)
25.08 ± 3.88
ASA score
Class 1
0 (0.0%)
Class 2
8 (57.1%)
Class 3
6 (42.9%)
Cirrhosis
Yes
0 (0.0%)
Indication of extended hepatectomy
Benign liver disease
2 (11.8%)
Primary malignancy
9 (52.9%)
Cholangiocarcinoma
9 (100%)
Hepatocellular carcinoma
0 (0.0%)
Metastatic disease
6 (35.3%)
Preoperative chemotherapy
Yes
5 (29.4%)
Preoperative platelet count (x 109/L)
Mean (SD)
122.3 ± 22.3
Intraoperative blood loss (ml)
3352.94 ± 2019.32
Transfusion of RBC
Patient
8 (50.0%)
Unit
4.38 ± 6.26
Transfusion of FFP
Patient
9 (56.3%)
Unit
4.31 ± 5.91
Operation time (min)
381.29 ± 136.05
PHLF
10 (58.8%)
Grade A
0 (0.0%)
Grade B
2 (20.0%)
Grade C
8 (80.0%)
Major morbidity
6 (35.3%)
ICU stay (days)
16.65 ± 9.50
Hospitalization (days)
30.18 ± 15.20
30-day mortality
6 (35.3%)
BMI: body mass index; ASA: American Society of Anesthesiologists; SD: standard deviation; RBC: red blood cells; FFP: fresh-frozen plasma; PHLF: posthepatectomy liver failure; ICU: intensive care unit. Based on the ISGLS definition. Grades III and IV based on the Clavien-Dindo classification.
