Canadian Journal of Gastroenterology and Hepatology / 2018 / Article / Tab 2

Research Article

Management Strategies and Outcomes for Hyponatremia in Cirrhosis in the Hyponatremia Registry

Table 2

Clinical characteristics of cirrhosis patients admitted with HN subdivided by hyponatremia severity.

Total
N = 518
[Na+], mmol/L
<120
n = 106
≥120–≤125
n = 202
>125–≤130
n = 210

Median age, y56545657
Male/female, n345/17373/33130/72142/68
BUN, mg/dL20.0 (19.0)18.0 (20.5)21.0 (20.0)19.0 (17.0)
Cr, mg/dL1.0 (0.6)1.0 (0.7)1.1 (0.7)1.0 (0.6)
BUN:Cr ratio18.9 (10.4)19.0 (12.0)19.8 (11.6)18.0 (9.1)
Alb, g/dL2.5 (0.8)2.6 (1.1)2.5 (0.8)2.4 (0.6)
Tbili, µmol/L4.3 (7.4)4.3 (7.2)4.5 (6.9)4.3 (7.6)
INR, s1.7 (0.6)1.6 (0.5)1.7 (0.7)1.7 (0.7)
Severe ascites, n (%)284 (55)53 (50)124 (61)107 (51)
Severe HE, n (%116 (22)30 (28)51 (25)35 (17)
C-P score11.0 (3.0)10.5 (3.0)11.0 (3.0)10.0 (3.0)
MELD score20.2 (9.7)18.7 (9.0)20.8 (8.0)20.2 (10.4)
MELD-Na score27.3 (6.3)26.7 (5.6)28.0 (5.0)26.3 (7.6)

< 0.01.
Values for blood urea nitrogen (BUN), creatinine (Cr), BUN:Cr ratio, albumin (Alb), total bilirubin (Tbili), international normalized ratio (INR), and Child-Pugh (CP), Model for End-Stage Liver Disease (MELD), and MELD-NA scores are median (interquartile range). HE, hepatic encephalopathy; HN, hyponatremia.

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