Research Article
Efficacy and Safety of Immunosuppressive Therapy for PBC–AIH Overlap Syndrome Accompanied by Decompensated Cirrhosis: A Real-World Study
Table 3
Histological features of the decompensated PBC-AIH patients.
| Variables | UDCA-only group (N=14) | UDCA+IS group (N=14) | P value |
| Number of portal areas | 10 | 9 | 0.541 | Severe interface hepatitis | 0/14 | 2/14 | 0.481 | Moderate interface hepatitis | 14/14 | 12/14 | 0.481 | Hepatocyte rosette formation | 8/14 | 10/14 | 0.695 | Lymphoplasmacytic infiltrate | 13/14 | 13/14 | >0.999 | Emperipolesis | 0/14 | 0/14 | - | Bile duct damage | 13/14 | 10/14 | 0.326 | Ductopenia | 9/14 | 6/14 | 0.449 | Bile duct proliferation | 11/14 | 9/14 | 0.678 | Cholestasis | 7/14 | 6/14 | >0.999 | G0/1/2/3/4 (N) | 0/0/2/12/0 | 0/1/2/7/4 | 0.374 | S0/1/2/3/4 (N) | 0/3/4/5/2 | 0/0/3/8/3 | 0.117 |
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Note. UDCA, ursodeoxycholic acid; IS, immunosuppressants.
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