Domino Hepatocyte Transplantation: A Therapeutic Alternative for the Treatment of Acute Liver Failure

Figure 1

Each year a large number of livers from cadaverous donors are rejected for transplantation. The causes include a high degree of steatosis, no heart beating, and nonviral cirrhosis. These organs rejected for orthotopic transplantation have been object of studies and sources of great importance for obtaining liver cells for cell transplantation. The hepatocyte isolation with quality from these organs associated with cryopreservation technique will allow the development of a bank of liver cells that are available for the treatment of a large number of patients with ALF.