Macroscopic Portal Vein Thrombosis in HCC Patients
Table 3
Logistic regression model of PVT (No/Yes), on single variables (A), all as categories. Final multiple logistic regression model in stepwise method of PVT (No/Yes), on all variables as categories, included together in the model (B). Combination of MTD (<5.0/≥5.0), focality (Unifocality/Multifocality), and AFP (≤100/>100) (C).
Parameter
OR
se(OR)
p-value
95% C.I.
(A)
MTD (cm)
<5.0 [Ref. category]
1
≥5.0
3.97
0.53
<0.001
3.05 to 5.17
Tumor Nodule #
Unifocality (n=1) [Ref. category]
1
Multifocality (n≥2)
2.43
0.31
<0.001
1.90 to 3.11
AFP (IU/mL)
≤100 [Ref. category]
1
>100
2.55
0.32
<0.001
2.00 to 3.25
(B)
MTD (cm)
<5.0 [Ref. category]
1
≥5.0
3.49
0.48
<0.001
2.66 to 4.57
Tumor Nodule #
Unifocality (n=1) [Ref. category]
1
Multifocality (n≥2)
2.22
0.29
<0.001
1.71 to 2.88
AFP (IU/mL)
≤100 [Ref. category]
1
>100
2.05
0.27
<0.001
1.58 to 2.65
(C)
Combination of: MTD, Focality, and AFP
MTD<5.0 & Unifocality & AFP≤100 [Ref. category]
1
MTD<5.0 & Unifocality & AFP>100
2.80
0.82
<0.001
1.57 to 4.99
MTD<5.0 & Multifocality & AFP≤100
2.17
0.71
0.02
1.15 to 4.11
MTD<5.0 & Multifocality & AFP>100
6.93
2.31
<0.001
3.60 to 13.31
MTD≥5.0 & Unifocality & AFP≤100
4.68
1.20
<0.001
2.83 to 7.73
MTD≥5.0 & Unifocality & AFP>100
7.48
1.92
<0.001
4.52 to 12.38
MTD≥5.0 & Multifocality & AFP≤100
9.50
2.76
<0.001
5.37 to 16.80
MTD≥5.0 & Multifocality & AFP>100
17.94
4.80
<0.001
10.62 to 30.30
OR, odds ratio; se(OR), standard error of odds ratio; PVT, portal vein thrombosis; MTD, maximum tumor diameter; AFP, alpha-fetoprotein.
