Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis

Table 3

Results of meta-regression for cirrhosis.

Covariate	Number	Pooled sensitivity	value	Pooled specificity	value	Joint value
Classification criteria
METAVIR score	28	0.82 (0.77–0.87)	<0.01	0.88 (0.85–0.91)	<0.01	0.17
Non-METAVIR score	13	0.89 (0.83–0.94)		0.86 (0.80–0.91)
Interval time
On the next day of liver biopsy	13	0.79 (0.71–0.86)	<0.01	0.88 (0.84–0.93)	<0.01	0.21
More than one day after liver biopsy	28	0.86 (0.82–0.90)		0.87 (0.83–0.90)
Average sample size
⩾20 mm	8	0.79 (0.69–0.89)	<0.01	0.88 (0.83–0.94)	<0.01	0.47
Not ⩾ 20 mm	33	0.85 (0.81–0.89)		0.87 (0.84–0.90)
Region
Asian	31	0.86 (0.81–0.90)	<0.01	0.86 (0.83–0.89)	<0.01	0.12
Caucasian	10	0.78 (0.67–0.88)		0.91 (0.86–0.95)