Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation

Table 2

Comparison of laboratory data between A-AIH and C-AIH patients.

	Acute; (40.0%)	Chronic; (60.0%)
HGB (g/L)			0.687
PLT (10^9/L)	112 (76, 169)	121 (76, 160)	0.757
WBC (10^9/L)	5.24 (3.51, 6.43)	4.50 (3.72, 5.69)	0.556
TB (µmol/L)	93 (48.1, 198.9)	17.8 (13.5, 24.3)	<0.001
DB (µmol/L)	83.2 (30.3, 157.4)	6.7 (4.7, 11.3)	<0.001
ALT (IU/L)	330 (149, 452)	42 (22, 97)	<0.001
AST (IU/L)	394 (208, 557)	45 (34, 87)	<0.001
AST/ALT	1.21 (0.98, 1.74)	1.13 (0.94, 1.65)	0.694
ALB (g/L)			<0.001
GLB (g/L)	42.7 (35.8, 47)	35.8 (31.4, 41.3)
ALP (IU/L)	144 (125, 173)	98 (80, 146)	<0.001
GGT (IU/L)	128 (63, 225)	58 (27, 110)
PT (s)	14.7 (13.2, 16.3)	12.8 (11.9, 13.4)	<0.001
INR	1.27 (1.12, 1.39)	1.09 (1.01, 1.13)	<0.001
IgG (g/L)	30.8 (21.5, 33.2)	19.3 (16, 24.7)	<0.001
ANA
<1 : 100	4 (12.5%)	21 (44.7%)
≥1 : 100	28 (87.5%)	26 (55.3%)
AMA
−	27 (84.4%)	43 (97.7%)	0.322
+	5 (15.6%)	1 (2.3%)
LKM
−	32 (100%)	43 (97.7%)	1.000
+	0	1 (2.3%)
LC-1
−	32 (100%)	43 (97.7%)	1.000
+	0	0
	0	1 (2.3%)
SLA
−	31 (96.9%)	41 (93.2%)	1.000
+	1 (3.1%)	3 (6.8%)
ANCA
−	14 (77.8%)	19 (79.2%)	0.178
+	2 (11.1%)	0
	2 (11.1%)	5 (20.8%)
Coombs
−	6 (42.9%)	14 (66.7%)	0.091
+	8 (57.1%)	6 (28.5%)
	0	1 (4.8%)

. AIH: autoimmune hepatitis; IAIHG: international autoimmune hepatitis group; HGB: haemoglobin; PLT: platelet; WBC: white blood cell; TB: total bilirubin; DB: direct bilirubin; ALT: alanine aminotransferase; AST: aspartate transaminase; ALB: albumin; GLB: globulin; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase; PT: prothrombin time; INR: international normalized ratio; IgG: immunoglobulin G; ANA: anti-nuclear antibody; AMA: anti-mitochondrial antibody; LKM: liver kidney microsomal; LC: liver cytosol; SLA: soluble liver antigen; ANCA: anti-neutrophil cytoplasmic antibody; Coombs: Coombs test.