Clinical Study
Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation
Table 3
Comparison of histological features between A-AIH and C-AIH patients.
| | Acute
| Chronic
| |
| G | | | | 0 | 0 | 1 (2.1%) | <0.001 | 1 | 1 (3.3%) | 12 (25.0%) | 2 | 2 (6.7%) | 17 (35.4%) | 3 | 21 (70.0%) | 18 (37.5%) | 4 | 6 (20.0%) | 0 |
| S | | | | 0 | 0 | 2 (4.2%) | 0.135 | 1 | 10 (33.3%) | 20 (41.7%) | 2 | 3 (10.0%) | 10 (20.8%) | 3 | 7 (23.3%) | 4 (8.3%) | 4 | 10 (33.3%) | 12 (25.0%) |
| Lobular inflammation | | | | 0 | 0 | 2 (4.2%) | | 1 | 17 (56.7%) | 40 (80.3%) | 2 | 6 (20.0%) | 2 (4.2%) | 3 | 7 (23.3%) | 4 (8.3%) |
| Interface inflammation | | | | 0 | 4 (13.3%) | 13 (27.1%) | | 1 | 5 (16.7%) | 21 (43.8%) | 2 | 14 (46.7%) | 11 (22.9%) | 3 | 7 (23.3%) | 3 (6.3%) |
| Hepatocyte rosettes | | | | No | 2 (6.7%) | 21 (43.8%) | <0.001 | Yes | 28 (93.3%) | 27 (56.3%) |
| Periportal lymphocyte | | | | 0 | 0 | 0 | <0.001 | 1 | 1 (3.3%) | 19 (39.6%) | 2 | 29 (96.7%) | 29 (60.4%) |
| Periportal plasmocyte | | | | 0 | 1 (3.3%) | 17 (35.4%) | <0.001 | 1 | 15 (50.0%) | 27 (56.3%) | 2 | 14 (46.7%) | 4 (8.3%) |
| Periportal neutrophils | | | | 0 | 8 (26.7%) | 28 (58.3%) | | 1 | 12 (40.0%) | 16 (33.3%) | 2 | 10 (33.3%) | 4 (8.3%) |
| Periportal monocyte | | | | 0 | 0 | 0 | <0.001 | 1 | 1 (3.3%) | 19 (39.6%) | 2 | 29 (96.7%) | 29 (60.4%) |
| Periportal eosinocyte | | | | 0 | 13 (43.3%) | 36 (75.0%) | | 1 | 17 (56.7%) | 12 (25.0%) | 2 | 0 | 0 |
| Bile duct injury | | | | 0 | 5 (16.7%) | 31 (64.6%) | <0.001 | 1 | 21 (70.0%) | 17 (35.4%) | 2 | 4 (13.3%) | 0 |
| Centrilobular necrosis | | | | No | 20 (66.7%) | 44 (91.7%) | | Yes | 10 (33.3%) | 4 (8.3%) |
| Lobular neutrophils | | | | 0 | 8 (26.7%) | 40 (83.3%) | < | 1 | 10 (33.3%) | 5 (10.4%) | 2 | 12 (40.0%) | 3 (6.3%) |
| Lobular monocyte | | | | 0 | 8 (26.7%) | 39 (81.3%) | <0.001 | 1 | 11 (36.7%) | 7 (14.6%) | 2 | 11 (36.7%) | 2 (4.2%) |
| Lobular eosinocyte | | | | 0 | 19 (63.3%) | 44 (91.7%) | | 1 | 10 (33.3%) | 4 (8.3%) | 2 | 1 (3.3%) | 0 |
| Eosinophilic body | | | | No | 22 (73.3%) | 44 (91.7%) | 0.05 | Yes | 8 (26.7%) | 4 (8.3%) |
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