Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children

Table 1

Analyzed parameters in all obese patients included in the study.

Parameters	NAFLD; median; Q1–Q3; ()	Non-NAFLD; median; Q1–Q3; ()
Gender, M/F	33/6	51/18	NS
IL-18 (pg/ml)	335; 257–493	299; 219–383	0.034
BMI (kg/m^2)	29; 27–34	27; 25–31	0.007
Waist (cm)	100; 94–108	93; 86–103	0.008
ALT (IU/l)	64; 50–101	26; 19–33	0.000
AST (IU/l)	39; 32–52	25; 21–30	0.000
GGT (IU/l)	30; 23–45	18; 14–23	0.000
Bilirubin (mg/dl)	0.6; 0.5–0.9	0.6; 0.45–0.7	NS
Total cholesterol (mg/dl)	177; 153–216	174; 145–190	NS
HDL-C (mg/dl)	44; 39–51	46; 38–54	NS
LDL-C (mg/dl)	97; 79–143	99; 78–116	NS
TG (mg/dl)	132; 85–173	108; 85–142	NS
Glucose (mg/dl)	93; 85–99	91; 86–96	NS
Insulin (μIU/ml)	18; 14–22	15; 11–18	0.011
HOMA-IR	4.2; 3.2–5.8	3.2; 2.1–4	0.005
Uric acid (mg/dl)	6.5; 5.5–7.4	5.7; 4.8–6.6	0.023
hsCRP (mg/l)	0.9; 0.7–1.8	1.3; 0.6–2	NS
Ferritin (ng/ml)	61; 50–105	52; 34–65	0.005
A1AT (g/l)	1.3; 1.2–1.5	1.4; 1.2–1.5	NS
USG grade of steatosis	2; 1–3	1; 0-1	0.000
^1HMRS (r.u.)	163; 106–210	80; 40–148	0.000