Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children

Table 3

Comparison of obese children without liver steatosis and with advanced liver steatosis evaluated in USG according to Saverymuttu et al.

Parameters	No liver steatosis; USG grade 0; median; Q1–Q3; ()	Advanced liver steatosis; USG grade 2-3; median; Q1–Q3; ()
Gender, M/F	12/7	36/6	NS
IL-18 (pg/ml)	279; 198–320	335; 249–443	0.027
BMI (kg/m^2)	27; 25–30	28; 27–33	NS
Waist (cm)	90; 83–98	99; 93–107	0.014
ALT (IU/l)	20; 16–31	48; 36–77	0.000
AST (IU/l)	23; 20–29	32; 26–45	0.000
GGT (IU/l)	18; 13–23	27; 21–35	0.000
Bilirubin (mg/dl)	0.6; 0.5–0.7	0.6; 0.4–0.85	NS
Total cholesterol (mg/dl)	164; 137–182	170; 153–191	NS
HDL-C (mg/dl)	47; 39–56	42; 37–50	NS
LDL-C (mg/dl)	92; 73–111	96; 79–121	NS
TG (mg/dl)	86; 65–116	120; 88–167	0.004
Glucose (mg/dl)	90; 83–96	95; 90–99	NS
Insulin (μIU/ml)	14; 8–17	17; 12–21	NS
HOMA-IR	3.2; 1.9–3.7	3.9; 3–5.4	0.020
Uric acid (mg/dl)	5.9; 4.8–7	6.7; 5.6–7.3	NS
hsCRP (mg/l)	1.1; 0.7–2.2	1.1; 0.5–1.7	NS
Ferritin (ng/ml)	54; 29–66	58; 46–85	NS
A1AT (g/l)	1.4; 1.2–1.6	1.3; 1.2–1.4	NS
^1HMRS (r.u.)	38; 17–61	172; 123–216	0.000