Research Article

Notch Signaling Pathway Is Inhibited in the Development of Barrett’s Esophagus: An In Vivo and In Vitro Study

Figure 2

Representative Hes1 immunohistochemical staining in samples with different histological alterations. Intense Hes1 protein was mainly expressed in cytoplasm and nucleus of normal esophageal cells, and metaplastic columnar cells mainly exhibited negative staining (arrows). Scale bar in the figure is 40 μm. Magnified figures were shown in the right side.