Clinical Study

Pathological Features of Mitochondrial Ultrastructure Predict Susceptibility to Post-TIPS Hepatic Encephalopathy

Table 1

Perioperative clinical characteristics of two groups.

ItemsGroup AGroup Bt/χ2P

Patient (n)7842
Gender (M/F, n)54/2430/120.0630.802
Age (mean ± SD, years)54.2±8.1852.9±9.130.7750.440
CTP (n, %)6.7530.056
 Stage A39 (50.0)25 (59.5)
 Stage B24 (30.8)13 (31.0)
 Stage C15 (19.2)4 (9.5)
MELD score7.04±3.218.23±4.831.2500.214
ALT (U/L)28.6±14.428.0±15.40.2150.830
AST (U/L)47.7±12.645.3±13.20.3420.647
Ammonia (mean ± SD, μmol/L)50.4±17.064.8±29.31.7410.306
PPG (mean ± SD, mmHg)
 Before shunt26.0±4.6725.7±4.820.4310.668
 After shunt15.1±4.3115.2±4.100.0300.976
PPG reduction (mean ± SD, mmHg)10.9±2.6010.5±2.510.8410.402

ALT: alanine transaminase; AST: aspartate aminotransferase; CTP: Child-Pugh stage; MELD: model for end-stage liver disease; PPG: portal pressure gradient.