Figure 3: Hematoxylin-eosin staining of spleen sections of N. oleander leaves decoction induced APR in rats after 3 (b), 12 (c), and 24 h (d) time course with sterile muscle abscess compared with control (a). Fully developed splenic follicle (F), the periarteriolar lymphoid sheath (PALS), white pulp (WP), red pulp (RP), central artery (A), and the marginal zone shown by black arrow and depopulation is represented with arrow heads. (magnification: 100x; inset 400x).