Immunohistochemical Coexpression of Epithelial Cell Adhesion Molecule and Alpha-Fetoprotein in Hepatocellular Carcinoma

Table 1

Demographic and clinicopathological characteristics in patients with hepatocellular carcinoma.

Variable	Descriptive Statistic (%)	P value
Gender
Female	13 (31.71)	0.019
Male	28 (68.29)
Age
Mean (Standard Deviation)	59.2 (9.5)	N/A
Median (IIQ)	59 (54;66)
Minimum; Maximum	25; 75
Comorbidities
No	22 (53.65)	0.357
Yes	19 (46.34)
Etiology
Idiopathic	7 (17.07)	0.241
Alcohol	5 (12.20)	0.058
Virus B	12 (29.26)	0.528
Virus C	17 (41.46)	0.015
Serum AFP (ng / mL)
Mean (Standard Deviation)	1864.1 (9266.3)	N/A
Median (IIQ)	59 (54;66)
Minimum; Maximum	1.9; 59900
Serum AFP (ng / mL)
Less than 100	26 (63.41)	0.001
100 to 400	7 (17.07)	0.027
Greater than 400	8 (15.51)	0.061
Surgical procedure
Minor hepatectomy	28 (68.29)	0.019
Larger hepatectomy	13 (31.71)
Nodule
Single nodule	32 (78.0)	<0.001
Multiple	9 (22,0)
Diameter
≤ 5 cm	23 (56.1)	0.357
> 5 cm	18 (43.9)
TNM Staging
I	18 (43.9)	0.150
II	17 (41.5)	0.268
III	6 (14.6)	0.011
Angiolymphatic invasion
No	24 (58.5)	0.584
Yes	17 (41.5)
Histological differentiation
Well	19 (46.3)	0.077
Moderate	18 (43.9)	0.150
Poor	4 (9.8)	0.001
AFP in HCC
Negative	29 (70.7)	0.008
Positive	12 (29.3)
EpCAM in HCC
Negative	29 (70.7)	0.008
Positive	12 (29.3)

Note: a homogeneity test was performed between the categories; p <0.10; p <0.05; p <0.01.