Clinical Study

Gastric Peroral Endoscopic Myotomy (G-POEM) as a Treatment for Refractory Gastroparesis: Long-Term Outcomes

Table 2

Demographic features, clinical features, and follow-up.

Age (years, median (range))63.5 (26-82)
Gender (ratio, male/female)11/5
Aetiology of gastroparesis
 Postsurgical13 (81.2%)
 Diabetic3 (18.8%)
Duration of disease before G-POEM (months, median (range))22 (2-84)
Previous therapy
 PPIs16 (100%)
 Metoclopramide14 (87.5%)
 Nasojejunal nutrition tube5 (31.3%)
GCSI score (mean (±SD)) before G-POEM
 Nausea3.37±1.59
 Retching2.56±1.82
 Vomiting3.75±1.61
 Stomach fullness3.13±1.67
 Not able to finish a normal-sized meal4.06±1.18
 Feeling excessively full after a meal3.31±1.54
 Loss of appetite1.94±1.98
 Bloating1.94±1.88
 Stomach or belly visibly large0.19±0.75
 Total24.25±5.47
Gastric emptying scintigraphy before G-POEM
 Half emptying time (min, mean (±SD))183.20±77.39
 Retention at 2 hours (mean (±SD))69.33±11.46%
Technical success rate100%
Procedure time (min, mean (±SD))45.25±12.96
Closure of mucosal incision
 Metal clip13 (81.2%)
 Overstitch3 (18.8%)
Hospital stay (days, median (range))6 (4-10)
Intraoperative adverse events0
Follow-up time (months, median (range))14.5 (5-19)
Total GCSI score (mean (±SD)) after G-POEM6.37±6.34
Gastric emptying scintigraphy (n=8) after G-POEM
 Half emptying time (min, mean (±SD))83.98±34.65
 Retention at 2 hours33.38±18.17%
Long-term clinical remission13 (81.3%)

G-POEM: gastric per oral endoscopy myotomy, GSCI: Gastroparesis Cardinal Symptom Index.