Review Article

Economic Evaluations of Treatments for Inflammatory Bowel Diseases: A Literature Review

Table 1

Study Characteristics.

Number of studies (%)

Type of analysisn (%)
 CUA40 (83) 
 CEA5 (10) 
 CMA3 (6)
Study population
 UC27 (56) 
 CD20 (42) 
 Both CD and UC1 (2)
Type of treatments under investigation
 Biologic treatments33 (69) 
 5-ASA11 (23) 
 Immunosuppressant 5 (10) 
 Surgery 2 (4) 
 GMA1 (2)
Study perspective
 Healthcare system perspective47 (98) 
 Societal1 (2)
Time horizon
 ≤1 year24 (50) 
 2–5 years11 (23) 
 6–10 years4 (8) 
 30 years2 (4) 
 Lifetime4 (8) 
 Not reported3 (6)
Model structure
 Markov model24 (50) 
 Decision tree16 (33) 
 Markov and decision tree2 (4) 
 No model 4 (8) 
 Not reported2 (4)

CUA: cost-utility analysis; CEA: cost-effectiveness analyses; CMA: cost-minimisation analysis; GMA: granulocyte-monocyte aphaeresis; UC: ulcerative colitis; CD: Crohn’s disease; 5-ASA: 5-aminosalicylic acid.