Research Article
Ultrasound Grade of Liver Steatosis Is Independently Associated with the Risk of Metabolic Syndrome
Table 2
Relationship between ultrasound grade of liver steatosis and clinical features of patients from the final cohort (N=159).
| | | Normal liver | Mild steatosis | Moderate to severe steatosis | P-value for trend |
| | Number | 71 | 52 | 36 | - | | Age, years (median, IQR) | 60 (47 - 69.5) | 56.5 (48 - 67.5) | 59.5 (53.25 - 65.25) | 0.862 | | Sex (Male) (N, %) | 23 (32.4%) | 22 (42.3%) | 15 (41.7%) | 0.281 | | BMI, kg/m2 (median, IQR) | 25.4 (22.9 - 27.8) | 28.5 (25.2 - 32) | 32.6 (28.02 - 35.85) | <0.001 | | Obesity (N, %) | 11 (15.5%) | 21 (40.4%) | 22 (61.1%) | <0.001 | | IGM (N, %) | 8 (11.3%) | 14 (26.9%) | 12 (33.3%) | 0.005 | | Atherogenic dyslipidaemia (N, %) | 18 (25.4%) | 25 (48.1%) | 22 (61.1%) | <0.001 | | Raised blood pressure (N, %) | 24 (33.8%) | 33 (63.5%) | 23 (63.9%) | 0.001 | | Presence of MS (N, %) | 3 (4.2%) | 12 (23.1%) | 16 (44.4%) | <0.001 | | Number of components of MS (median, IQR) | 1 (0 - 1) | 2 (1 - 2) | 2 (1 - 3) | <0.001 | | AST (IU/L) (median, IQR) | 22 (17.5 - 24) | 21 (15.8 - 26.5) | 24 (20 - 30.25) | 0.096 | | ALT (IU/L) (median, IQR) | 19 (13 - 24.5) | 20.5 (16 - 26.8) | 20.5 (17 - 29.5) | 0.051 | | Bilirubin (mmol/L) | 12 (10 - 14) | 13.4 (10.3 - | 13.1 (10.05 - | 0.115 | | (median, IQR) | | 15.2) | 15.375) | | | GGT (IU/L) (median, IQR) | 22 (15 - 35) | 24.5 (17.8 - 38.5) | 25.5 (18.75 - 33.5) | 0.083 | | ALP (IU/L) (median, IQR) | 68 (57.5 - 78) | 71.5 (60 - 84) | 71.5 (56 - 86.25) | 0.334 | | Plt (x109/L) (median, IQR) | 234 (198.5 - 274) | 244 (200.3 - 318) | 251 (218.25 - 301) | 0.169 | | FIB4 (IU/L) (median, IQR) | 1.2 (0.9 - 1.7) | 1 (0.8 - 1.5) | 1.2 (1.026 - 1.587) | 0.739 |
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statistically significant at P<0.05 BMI: body mass index; dyslipidemia: triglycerides>upper limit of normal or high-density lipoprotein (HDL)<lower limit of normal; MS: metabolic syndrome; obesity: BMI>30 kg/m2; IQR: interquartile range; IGM: impaired glucose metabolism; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: gamma-glutamyl transferase; ALP: alkaline phosphatase; Plt: platelet count, FIB4: fibrosis-4 index, RBP: raised blood pressure. Mild steatosis: ultrasound grade 1; moderate to severe steatosis: ultrasound grades 2 and 3. |
