Research Article
Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy
Table 1
Baseline characteristics of 2,717 enrolled subjects with chronic liver disease alcohol related in Italy, by year of recruitment.
| Characteristic | Overall | Study 2001 | Study 2014 | p-value | (n=2,717) | (n=2,342) | (n=375) |
| Age, years, mean ± SD | | | | <0.001 |
| Sex Ratio (M/F) | 3.1 | 3.8 | 1.3 | <0.001 |
| BMI, mean ± SD | | | | 0.015 |
| Area of birth | | | | | (i) Northern/Central Italy | 1,295 (47.7%) | 1,099 (46.9%) | 196 (52.3%) | <0.001 | (ii) Southern Italy/Islands | 1,354 (49.8%) | 1,192 (50.9%) | 159 (42.4%) | | (iii) Born abroad | 71 (2.6%) | 51 (2.2%) | 20 (5.3%) | |
| Risk factors | | | | | (i) Alcohol intake alone | 1,163 (42.8%) | 983 (42.0%) | 179 (47.7%) | 0.02 | (ii) Alcohol intake/HBsAg positive | 172 (6.3%) | 140 (6.0%) | 32 (8.5%) | | (iii) Alcohol intake/anti-HCV positivity | 1,313 (48.3%) | 1,157 (49.4%) | 154 (41.1%) | | (iv) Alcohol intake/HBsAg positive/anti-HCV positive | 72 (6.3%) | 62 (2.6%) | 10 (2.7%) | |
| Diagnosis | | | | | (i) Chronic hepatitis | 1,762 (64.8%) | 1,550 (66.1%) | 212 (56.5%) | <0.001 | (ii) Liver cirrhosis without HCC | 834 (30.7%) | 697 (29.8%) | 137 (36.5%) | | (iii) Liver cirrhosis with HCC | 121 (4.5%) | 95 (4.1%) | 26 (6.9%) | |
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BMI: body mass index. HCC: hepatocellular carcinoma.
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