Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy

Table 2

Characteristics of 2,717 enrolled subjects with chronic liver disease alcohol related in Italy, by sex.

Characteristics	Males	Females	Sex Ratio (M/F)	p-value
	(n=2,059)	(n=658)
Age, years, mean ± SD			-	<0.001
BMI, mean ± SD			-	0.001
Area of birth
(i) Northern/Central Italy	943 (45.8%)	352 (53.5%)	2.7	<0.001
(ii) Southern Italy/Islands	1,069 (51.9%)	282 (42.9%)	3.8
(iii) Born abroad	47 (2.3%)	24 (3.6%)	2.0
Risk factors
(i) Alcohol intake alone	810 (39.3%)	352 (53.5%)	2.3	<0.001
(ii) Alcohol intake/HBsAg positive	147 (7.1%)	25 (3.8%)	5.9
(iii) Alcohol intake/anti-HCV positivity	1,040 (50.5%)	271 (41.2%)	3.8
(iv) Alcohol intake/HBsAg positive/anti-HCV positive	62 (3.0%)	10 (1.5%)	6.2
Diagnosis
(i) Chronic hepatitis	1,348 (65.5%)	414 (62.9%)	3.3	0.15
(ii) Liver cirrhosis without HCC	614 (29.8%)	220 (33.4%)	2.8
(iii) Liver cirrhosis with HCC	97 (4.7%)	24 (3.6%)	4.0

BMI: body mass index. HCC: hepatocellular carcinoma.