Research Article

Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy

Table 4

Characteristics of chronic liver diseases alcohol related in female sex over time, in Italy.

Characteristics2001 Study 2014 Study p-value
(n°=490)(n°=168)

Age (years), mean ± SD<0.001

BMI (kg/m2), mean ± SD0.1

Area of origin
(i) Northern/Central Italy251 (51.2%)101 (60.1%)0.009
(ii) Southern Italy/Islands225 (45.9%)57 (33.9%)
(iii) Born abroad14 (2.9%)10 (6.0%)

Risk factors
(i) Alcohol intake alone273 (55.7%)79 (47.0%)0.002
(ii) Alcohol intake/HBsAg positive11 (2.2%)14 (8.3%)
(iii) Alcohol intake/anti-HCV positivity200 (40.8%)71 (42.3%)
(iv) Alcohol intake/HBsAg positive/anti-HCV positive6 (1.2%)4 (2.4%)

Diagnosis
(i) Chronic hepatitis319 (65.1%)95 (56.5%)0.09
(ii) Liver cirrhosis without HCC156 (31.8%)64 (38.1%)
(iii) Liver cirrhosis with HCC15 (3.1%)9 (5.4%)

BMI: body mass index. HCC: hepatocellular carcinoma.