Research Article
Long Noncoding RNA GATA3-AS1 Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma by Suppression of PTEN, CDKN1A, and TP53
Table 1
The correlations between lncRNA GATA3-AS1 expression and clinicopathologic variables in patients with hepatocellular carcinoma.
| Variables | Cases | GATA3-AS1 | χ2 | | Low | High |
| Gender | | | | | | Male | 51 | 19 | 32 | 0.442 | 0.506 | Female | 29 | 13 | 16 |
| Age (years) | | | | | | <55 | 35 | 17 | 18 | 1.905 | 0.168 | ≥55 | 45 | 15 | 30 |
| Tumor size (cm) | | | | | | <5 | 26 | 16 | 10 | 7.445 | 0.006 | ≥5 | 54 | 16 | 38 |
| Differentiation | | | | | | Low | 46 | 17 | 29 | 1.838 | 0.372 | Moderate | 29 | 14 | 15 | High | 5 | 1 | 4 |
| Liver cirrhosis | | | | | | No | 23 | 9 | 14 | 0.010 | 0.920 | Yes | 57 | 23 | 34 |
| Lymph node metastasis | | | | | | No | 41 | 25 | 16 | 14.626 | <0.001 | Yes | 39 | 7 | 32 |
| Venous invasion | | | | | | No | 18 | 10 | 8 | 2.342 | 0.126 | Yes | 62 | 22 | 40 |
| TNM stage | | | | | | I + II | 27 | 17 | 10 | 8.954 | 0.003 | III + IV | 53 | 15 | 38 |
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LncRNA: long noncoding RNA, GATA3-AS1: GATA3 antisense RNA 1. . |