Research Article
The Association of HOTAIR with the Diagnosis and Prognosis of Gastric Cancer and Its Effect on the Proliferation of Gastric Cancer Cells
Table 1
Association of HOTAIR expression with clinical and pathologic features in GC patients.
| | Parameter | Total | HOTAIR | 2 | P | | Low | High |
| | Age (years) | | | | 1.662 | 0.197 | | ≤60 | 39(72.2%) | 11(20.3%) | 28(51.9%) | | | | >60 | 15(27.8%) | 7(13.0%) | 8(14.8%) | | Gender | | | | 0.000 | 1.000 | | Female | 18(33.3%) | 6(11.1%) | 12(22.2%) | | | | Male | 36(66.7%) | 12(22.2%) | 24(44.5%) | | Tumor size (cm) | | | | 0.947 | 0.331 | | <5 | 23(42.6%) | 6(11.1%) | 17(31.5%) | | | | ≥5 | 31(57.4%) | 12(22.2%) | 19(35.2%) | | Tumor differentiation | | | | 11.910 | 0.001 | | Well/moderate | 22(40.7%) | 10(18.5%) | 12(22.2%) | | | | Poor | 32(59.3%) | 8(14.8%) | 24(44.4%) | | Lymph node metastasis | | | 8.704 | 0.003 | | Negative | 16(29.6%) | 10(18.5%) | 6(11.1%) | | | | Positive | 38(70.4%) | 8(14.8%) | 30(55.6%) | | | | Distant metastasis | | | | 12.15 | 0.000 | | Negative | 30(55.6%) | 16(29.6%) | 14(25.9%) | | | | Positive | 24(44.4%) | 2(3.7%) | 22(40.7%) | | | | Clinical stage (TNM) | | | 6.000 | 0.014 | | I~II | 18(33.3%) | 10(18.5%) | 8(14.8%) | | | | III~IV | 36(66.7%) | 8(14.8%) | 28(51.9%) | | |
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