Ischemic Postconditioning (IPostC) Protects Fibrotic and Cirrhotic Rat Livers after Warm Ischemia
Figure 5
Lactate dehydrogenase, bile flow, and portal perfusion pressure in healthy livers after follow-up study ± IPostC. Warm ischemia in situ ± IPostC 4x60 sec was performed in the healthy livers of male SD rats. The perfusate of reperfusion was collected and subsequently used to perfuse additional healthy livers (postconditioned and nonpostconditioned, each with n=6). Lactate dehydrogenase (LDH) was measured in the perfusate and bile was collected during the time of perfusion. Both LDH and bile flow are shown as maximal (LDH (a); bile (c)) and total (LDH (b); bile (d)) values. The portal perfusion pressure (e) was monitored continuously and is represented as maximal value. Data are expressed as the mean ± SEM. Significant values are specified as p<0.05 and p<0.01.