Impact of Chronic Statins Use on the Development of Esophagitis in Patients with Gastroesophageal Reflux Disease

Table 2

Univariate analysis factors affect the presence of esophagitis comparing the control group to A-D groups and comparing initial (groups A and B) with the advanced (B and C) groups.

Variables	Control group	Groups A-D	P value	Groups A+B	Group C+D	P value
Active smokers (%)	47.2	77.5	<0.0001	76.9	86.3	0.02
Use of statins (%)	15.8	8	<0.0001	7.9	9	0.3
Use of NSAIDS (%)	27.1	33.6	<0.0001	35.2	33.5	0.3
Use of PPI (%)	46.5	69.5	<0.0001	69	76	0.08
Presence of hiatal hernia (%)	28.5	41.4	<0.0001	41.1	45.4	0.2
Presence of H. pylori (%)	66.4	70.4	0.02	69.7	80.6	0.06