Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases

Figure 3

Specimens obtained from the same pancreatic cancer lesion using both a conventional fine needle aspiration (FNA) needle (a, c) and a Franseen needle (b, d). The specimen obtained by the FNA needle shows many blood clots (a), whereas the specimen obtained by the Franseen needle shows good core tissues with low-power field magnification. (c) Scattered atypical cells can be identified in the blood clots with high-power field magnification, but they are insufficient for a cancer diagnosis. (d) A component of atypical cells with enlarged nuclei in the fibrous stroma is detected with high-power field magnification, consistent with ductal carcinoma of the pancreas.

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