Clinical Study
Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center
Table 1
Result of univariate analysis for baseline characteristics of 78 patients with mesenteric vascular thrombosis.
| | Variable | Intestinal necrosis
N=58(%) | NO intestinal necrosis
N=20(%) | Overall
N=78(%) | P value |
| | Patient demographics | | | | | | Age(years) | 60.8±16.4 | 61.4±13.3 | 60.9±15.5 | 0.880 | | Male/female | 38:20 | 16:4 | 54:24 | 0.273 | | BMI | 26.7± 2.6 | 24.0± 4.5 | 25.9±3.3 | 0.003 | | Atherosclerosis risk factors | | | | | | Tobacco use (%) | 42(72) | 12(60) | 54(69) | 0.583 | | Alcohol use (%) | 36(62) | 8(40) | 44(56) | 0.196 | | Dyslipidemia (%) | 28(48) | 4(20) | 32(41) | 0.176 | | Associated comorbidities | | | | | | Diabetes mellitus (%) | 16(28) | 4(20) | 20(26) | 0.569 | | Cardiac disease (%) | 26(79) | 8(40) | 34(44) | 0.797 | | Arterial hypertension (%) | 14(24) | 4(20) | 18(23) | 0.196 | | Chronic liver disease %) | 4(7) | 2(10) | 6(8) | 0.643 | | Venous thromboembolism (%) | 6(10) | 0 | 6(8) | 0.329 | | More than one comorbidity (%) | 16(28) | 2(10) | 18(23) | 0.133 | | Clinical signs on admission | | | | | | Mean pulse rate (bpm) | 105.7±27.7 | 101.1±10.9 | 104.5±24.5 | 0.474 | | Mean systolic blood pressure (mmHg) | 129.4±24.5 | 133.8±15.6 | 130.5±22.4 | 0.451 | | Gastrointestinal hemorrhage (%) | 12(21) | 4(20) | 16(21) | 0.612 | | Mean time between onset of symptoms and operation (hours) | 90.5±80.3 | 36.2±22.5 | 76.6±73.8 | 0.004 | | Organ failure (%) | 32(55) | 4(20) | 36(46) | 0.009 | | Peritonitis (%) | 44(76) | 6(30) | 50(64) | <0.001 | | Laboratory parameters | | | | | | Mean white blood cell count(9/L) | 17.1±6.6 | 15.3±4.7 | 16.7±6.2 | 0.253 | | Mean platelet count (9/L) | 197.6±81.3 | 186.3±94.5 | 194.7±83.7 | 0.603 | | Mean serum creatinine (umol/L) | 94.9±74.1 | 90.6±17.7 | 93.8±64.2 | 0.797 | | Mean serum albumin (g/L) | 37.1±7.5 | 35.7±4.1 | 36.7±6.8 | 0.436 | | Mean serum ALT(IU/L) | 117.9±517.2 | 26.7±18.3 | 109.4±479.7 | 0.471 | | Mean serum AST(IU/L) | 138.1±555.8 | 26.3±11.2 | 94.6±445.9 | 0.406 | | Mean serum lactate (mmol/L) | 2.1±0.4 | 1.6±0.3 | 2.0±0.5 | <0.001 | | Mean arterial pH | 7.31±0.1 | 7.39±0.1 | 7.3±0.1 | 0.001 | | International normalized ratio (INR) | 1.17±0.2 | 1.15±0.2 | 1.2±0.2 | 0.706 | | Dimer (mg/L) | 10.4±11.6 | 8.9±10.2 | 10.0±11.1 | 0.617 |
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BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate aminotransferase.
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