Research Article

Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma

Table 3

Correlation between p21, p53, and p53 serine-P expression in HCC.

p21p53p53 Ser15-Pp53 Ser392-P

Correlation10.1910.3090.018
p21coefficient
P  0.007≤0.0010.801

Correlation0.19110.1570.485
p53coefficient
P  0.0070.027≤0.001

Correlation0.4080.2570.2390.100
PCNAcoefficient
P  ≤0.001≤0.0010.0010.162

Spearman’s rank correlation coefficient and correlation significance of the proteins. Protein expression score was used to calculate Spearman’s rank correlation coefficient and significance; correlation coefficient, Spearman rank correlation coefficient; P value, Spearman correlation; , P < 0.05 (significant correlation); , P < 0.01 (highly significant correlation). Spearman’s rank correlation test.