Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma

Table 4

Correlation between p53, p53 serine-P, PCNA, and clinicopathological factors.

		Vascular invasion	Major portal vein invasion	Intrahepatic invasion	5-Year survival
	Correlation	0.130	0.142	0.136	0.063
p53	coefficient
		0.067	0.046	0.056	0.373
	Correlation	0.082	0.116	0.152	0.011
p53 Ser 392-P	coefficient
		0.251	0.103	0.032	0.873
	Correlation	-0.010	-0.037	-0.070	-0.161
p53 Ser 15-P	coefficient
		0.888	0.599	0.323	0.023
	Correlation	0.211	0.221	0.259	0.202
PCNA	coefficient
		0.003	0.002	≤0.001	0.004
	Correlation	0.331	0.356	0.405	1
5-Year Survival	coefficient
		≤0.001	≤0.001	≤0.001

Spearman’s rank correlation coefficient and P value between protein expression score and clinicopathological factors. Correlation coefficient, Spearman’s rank correlation coefficient; P value, Spearman’s correlation; , P < 0.05; , P < 0.01. Spearman’s rank correlation test.