Canadian Journal of Gastroenterology and Hepatology / 2019 / Article / Tab 5

Research Article

Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma

Table 5

Cox proportional hazard model analysis of p53, p53 Ser 392-P, p53 Ser 15-P, PCNA, age, sex, and clinicopathological factors.

Exp(BSignificanceCl (95.0%

p530.9040.3980.716-1.142

p53 Ser 392-P0.9250.6960.627-1.365

p53 Ser 15-P0.6140.0130.418-0.902

PCNA1.6080.0021.192-2.169

Age1.093≤0.0011.045-1.143

Sex1.0850.8530.456-2.584

Vascular invasion3.9770.0061.484-10.658

Major portal vein invasion6.289≤0.0012.744-14.412

Intrahepatic invasion3.823≤0.0011.970-7.420

Hazard ratio and significance in Cox proportional hazard model analysis. Hazard ratio, Exp(B); Exp(B) < 1 (hazard goes down when factor goes up), Exp(B) >1 (hazard goes up when factor goes up); 95% CIs lower & upper values; significance; P value; , P < 0.05 (significant correlation); , P < 0.01 (highly significant correlation). Cox proportional hazard model test.

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