Copper Mediates Anti-Inflammatory and Antifibrotic Activity of Gleevec in Hepatocellular Carcinoma-Induced Male Rats

Figure 5

Histological assessment of liver fibrosis in control (CN-) and experimentally induced liver cancer (CN+) rats and the effects of the CU+, ITB, and DSF and the combination of ITB+CU+ and ITB+DSF+ on collagen deposition. The extent of matrix deposition (yellow arrow) was measured by Masson’s trichrome staining of liver tissue sections from different rat groups.