Copper Mediates Anti-Inflammatory and Antifibrotic Activity of Gleevec in Hepatocellular Carcinoma-Induced Male Rats

Figure 6

Histological assessment of liver fibrosis in the experimentally induced liver cancer (CN+) rats. The extent of matrix deposition (yellow arrow) was measured by Masson’s trichrome ((a); X400) to show fibroblasts (yellow arrow), the periodic acid Schiff (PAS) stain ((b) X400) to show fibroblast (yellow arrow) and infiltrated inflammatory cells (red arrow), and reticulin ((c), (d) different microscopic filters; X200) to show reticular fibers deposition (green arrows) in liver tissue sections from only the second group (CN+).

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