Research Article

Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) in HCV-Positive Egyptian Patients Treated with Sofosbuvir

Table 1

Characteristics of the studied population before treatment.

CharacteristicsStudied group (n = 87)

Qualitative variables (no., %)
Gender
 Male26 (29.9%)
 Female61 (70.1%)

BMI
 18.5–24.920 (23%)
 25.0–29.948 (55.2%)
 30.0 and above19 (21.8%)

Diabetes
 Yes6 (6.9%)
 No81 (93.1%)

Hypertension
 Yes18 (20.7%)
 No69 (79.3%)

Liver
 Normal60 (69%)
 Cirrhotic27 (31%)

Quantitative variables (mean ± SD)
Age (years)50.18 ± 10.01
HCV RNA (copies/ml)925507 ± 1241001
Total bilirubin (mg/dl)0.88 ± 0.2
Serum albumin (mg/dl)4.32 ± 0.52
INR1.06 ± 0.08
AST (U/L)44.66 ± 18.2
ALT (U/L)49.2 ± 28.97
HB (g/dl)13.48 ± 1.4
Platelet (n × 103/μl)208.86 ± 66.02
Creatinine (mg/dl)0.9 ± 0.48
eGFR (ml/min per 1.73 m2)83.92 ± 20.18
FIB4 score1.7 ± 0.9
APRI score0.6 ± 0.39

BMI: body mass index; HCV RNA: hepatitis C virus-ribonucleic acid; INR: international normalization ratio; AST: aspartate aminotransferase; ALT: alanine aminotransferase; HB: hemoglobin; eGFR: estimated glomerular filtration rate; FIB4 : fibrosis four; APRI : AST to platelet ratio index.