Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model

Table 1

Correlation between fasting blood insulin (FBI) and hepatic sterol regulatory element-binding protein (SREBP1c) in non-prediabetic (NPD) rats, prediabetic control (PD), and prediabetic rats treated with BA in the presence or absence of dietary intervention. r = Pearson’s correlation coefficient, R² = coefficient of determination, and n = sample size.

Groups	Correlation analysis	Independent variable: FBI	Dependent variable: hepatic SREBP1c
NPD	r	0.8068	0.8068
	R^2	0.6510	0.6510
	n	6	6
	value	0.0524^NS	0.0524^NS
PD	r	−0.9144	−0.9144
	R^2	0.8361	0.8361
	n	6	6
	value	0.0107	0.0107
ND + MET	r	−0.8691	−0.8691
	R^2	0.7552	0.7552
	n	6	6
	value	0.0246	0.0246
HFHC + MET	r	−0.8869	−0.8869
	R^2	0.7866	0.7866
	n	6	6
	value	0.0185	0.0185
ND + BA	r	0.4651	0.4651
	R^2	0.2164	0.2164
	n	6	6
	value	0.3526^NS	0.3526^NS
HFHC + BA	r	−0.7381	0.7381
	R^2	0.5448	0.5448
	n	6	6
	value	0.0939^NS	0.0939^NS

^NSNot significant; .